J’hésite toujours lorsque des hommes veulent régler des questions féminines (rappelons que moins d’un député péquiste sur trois possède un vagin), et donc c’est avec incrédulité que je perçois ces énoncés qui veulent que la priorité en matière d’équité des genres serait la coiffure des fonctionnaires, alors que, par exemple, la santé sexuelle est absente du curriculum national.

J’hésite toujours lorsque des hommes veulent régler des questions féminines (rappelons que moins d’un député péquiste sur trois possède un vagin), et donc c’est avec incrédulité que je perçois ces énoncés qui veulent que la priorité en matière d’équité des genres serait la coiffure des fonctionnaires, alors que, par exemple, la santé sexuelle est absente du curriculum national.

Fonds de recherche du Québec highlights three stunning students as government slashes budget

If you support government funding for research in Quebec, please join the Je suis Michèle movement

Announcement of the February winners of the Étudiants-chercheurs étoiles Award

Montreal, February 4, 2013 – Québec’s Chief Scientist, Rémi Quirion, is pleased to announce the February winners of the Étudiants-chercheurs étoiles Award, a competition spearheaded by the three Fonds de recherche du Québec.

Award winner, Fonds Nature et Technologies

Michel Lavoie, PhD student in in environmental studies at INRS

Award-winning publication: Influence of Essential Elements on Cadmium Uptake and Toxicity in a Unicellular Green Alga: the Protective Effect of trace Zinc and cobalt concentrations. Published in Environmental Toxicology and Chemistry, 31(7):1445-52, July 2012.

Award winner, Fonds Santé

Jean-Baptiste Pingault, Postdoctoral student at Université de Montréal’s Department of Social and Preventive Medicine.

Award-winning publication: Childhood trajectories of inattention, hyperactivity and oppositional behaviors and prediction of substance abuse/dependence: a 15-year longitudinal population-based study. Published in Molecular Psychiatry, 06-2012.

Award winner, Fonds Société et Culture

Leslie Tomory, Postdoctoral student in history at McGill University.

Award-winning publication: Progressive Enlightenment: The Origins of the Gaslight Industry,1780–1820. Published by Cambridge: MIT Press, mars 2012.

In addition to promoting careers in research, the competition aims to recognize the exceptional research contributions of college and university students, postdoctoral fellows and members of professional bodies who are enrolled in advanced research training programs in the areas covered by the three Fonds de recherche du Québec.

Every month, each Fund will award $1000 to a student researcher. An overview of the recipient’s project and a photo of the recipient will be featured on the Web site www.frq.gouv.qc.ca.

Dr. Quirion sends his congratulations to the winners.

Cancer Rant

I had to tell someone I love last night that lemon juice will not cure his cancer. FUCK antiscientific rumours and false hope. They just distract from the best possible medical healthcare and the reality of the situation a person faces. Hundreds of thousands of people around the world are dedicating their lives, wholeheartedly, to a cure. They publish what they discover in books that anyone can read. When they find something that helps, we all know about it, including front line doctors. There is no evil conspiracy to hide the cure, it’s not hidden a test-tube somewhere in a vault. I wish it was, because it wouldn’t take long for someone else to replicate the result anyway. Next time you see some FUCKING BULLSHIT on the Internet, don’t hesitate to stomp it out.

Researchers prevent autistic behaviours in mice

McGill and Université de Montréal researchers revealed yesterday that autism-like behaviors can be rectified in adult mice with compounds inhibiting protein synthesis, or with gene-therapy targeting neuroligins (a membrane protein that regulates synapse formation between neurons.) Their study is published in the journal Nature.

“The autistic behaviours in mice were prevented by selectively reducing the synthesis of one type of neuroligin and reversing the changes in synaptic excitation in cells,” explained Prof. Jean-Claude Lacaille at the University of Montreal’s Groupe de Recherche sur le Système Nerveux Central and Department of Physiology. “In short, we manipulated mechanisms in brain cells and observed how they influence the behaviour of the animal.” The researchers were also able to reverse changes in inhibition and augment autistic behaviors by manipulating a second neuroligin. “The fact that the balance can be affected suggests that there could be a potential for pharmacological intervention by targeting these mechanisms.”

“Since the discovery of neuroligin mutations in individuals with ASD in 2003, the precise molecular mechanisms implicated remain unknown,” said Christos Gkogkas, a postdoctoral fellow at McGill and lead author. “Our work is the first to link translational control of neuroligins with altered synaptic function and autism-like behaviors in mice. The key is that we achieved reversal of ASD-like symptoms in adult mice. Firstly, we used compounds, which were previously developed for cancer treatment, to reduce protein synthesis. Secondly, we used non-replicating viruses as vehicles to put a break on exaggerated synthesis of neuroligins.”

Autism spectrum disorders (ASD) encompass a wide array of neurodevelopmental diseases that affect three areas of behaviour: social interactions, communication and repetitive interests or behaviors. According to the U.S.-based Centers for Disease Control and Prevention, 1 in 88 children suffer from ASD, and the disorder is reported to occur in all racial, ethnic, and socioeconomic groups. ASDs are almost five times more common among boys (1 in 54) than among girls (1 in 252).

Links

To reach Dr. Lacaille

William Raillant-Clark
Media Relations 
Université de Montréal 
w.raillant-clark@umontreal.ca

Stephen Wilshire, an artist with autism, at work on a panorama of London. From his website.